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Experiments By Design (EbD) and Multivariate data analysis
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Figure shows output from a multivariate experiment design (MED)
of a protein formulation. Input variables are pH, ionic strength, and protein concentration with responses on protein
recovery and aggregation.
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HTD Biosystems provides courses in Design of Experiments (DOE) to biopharmaceutical companies. A 2 day course in Experiments by Design (EbD) provides sufficient information to the participants so that they can use DOE
effectively in Product Development. Please contact HTD Biosystems for additional information. A Short course in DOE for Pharmaceutical Scientists Feb 11-12th,
2010 Clarmont Hotel, Berkeley, CA Please
register at the link below. http://www.acteva.com/booking.cfm?bevaid=194492
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Experiments by Design provides
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- More information with the minimal number of experimental trials.
- Ranking of
critical process variables.
- Identification of specific interactions between variables.
- An empirical model
from the data that can be used for predicting process scenarios.
- Presentation of complex data in clear understandable
format.
- Statistical interpretation of the data.
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